Dave Asprey's Substack

Dave Asprey's Substack

The Mitochondrial Compound Tied to a Longer Lifespan

As long as you’re taking a form that works

Aug 01, 2026
∙ Paid

For years I took 30 to 40 mg a day of a supplement called PQQ, a cousin of CoQ10 that supports your mitochondria (the structures inside your cells that produce your energy), and felt nothing. The form I was taking turned out to be my problem. Once I fixed that, 10 mg did more than 40 mg ever had.

In the full version you’ll get:

  • The biological pathways behind PQQ’s effect on your brain and your mitochondria

  • What the human trials on cognition, sleep, and inflammation found

  • The newest data on PQQ

  • The absorption problem that cost me years and hundreds of dollars a month, and how to avoid making the same mistake

[Subscribe to unlock the full protocol]

User's avatar

Continue reading this post for free, courtesy of Dave Asprey.

Or purchase a paid subscription.
© 2026 Dave Asprey · Privacy ∙ Terms ∙ Collection notice
Start your SubstackGet the app
Substack is the home for great culture