Dave Asprey's Substack

Dave Asprey's Substack

Cocoa Extract Just Earned a Spot in the Longevity Stack

Forget everything you thought you knew about chocolate and heart health. A massive clinical trial just turned cocoa from dessert into legitimate cardiovascular medicine...

Nov 18, 2025
∙ Paid

The Numbers That Changed Everything

The COSMOS trial tracked 21,442 older adults for nearly four years. Half took a daily cocoa extract supplement. Half got a placebo. The results? A 27% reduction in cardiovascular deaths among those taking cocoa flavanols.

Not better markers. Not promising trends. Actual lives saved.

The supplement delivered 500 mg of cocoa flavanols daily, including about 80 mg of epicatechin - the key compound that makes this work. This wasn’t chocolate bars or hot cocoa. This was a standardized, tested extract that isolated the beneficial compounds while leaving the sugar and processing junk behind.

So how does cocoa effect inflammation?

This post is for paid subscribers

Already a paid subscriber? Sign in
© 2025 Dave Asprey
Privacy ∙ Terms ∙ Collection notice
Start your SubstackGet the app
Substack is the home for great culture